Since The list is ordered starting with the companies who invested the most in biotechnology. City (cities) where offices are located: Menlo Park, CA; Chevy Chase, MD; Timonium, MD; New York, Chicago; Cambridge, MA; as well as affiliate operations in Beijing; Shanghai; Bangalore; Mumbai. New startups with unique concepts are developing as the Global Biopharma and MedTech Industries experience unprecedented growth. PitchBook said more companies, especially large-sized technology startups, are expected to take the direct listing route to go public instead of an IPO in 2021. The firms unique model helps the portfolio companies direct access to the Fortune 500 execs or successful entrepreneurs. Managing Directors Thomas Ball and Michael Smerklo. Apeiron has more than 60 employees spread across five global locations. Founded in 2013, LiveOak Venture Partners is a venture capital firm headquartered in Austin, Texas. CFO Alyssa Dadoly, Partners Kip Mcclanahan, Mike Dodd, Morgan Flager, and Roger Chen. See: http://www.sec.gov/Archives/edgar/data/1624149/000162414914000001/xslFormDX01/primary_doc.xml Business Products and Services (B2B), Consumer Products and Services (B2C), Financial Services, Information Technology, Materials and Resources. Accel is a venture capital firm that concentrates on the following technology sectors: Consumer, Infrastructure, Media, Mobile, SaaS, Security, Customer care services, Enterprise software, and E-commerce. Venture capital in U.S. and Europe biotechnology industry 2015-2021 U.S. bioscience venture capital investments by segment 2018-2021 biotechnology funding by National Institutes for Health 2013-2023 After all, you cannot rush your way into building long-term relationships! The firm cited the presence in Cambridge of Pfizer and the planned move there of Baxter International. But two of those investment firms have emerged as major leaders, not only in the number of biotech funding rounds led, but also in overall dollars invested into the industry. 2 A $175 million fund focused on software and tech services, which closed in 2013, was to have been the 10th fund, but instead spun out of Morgenthaler by three of its partners under the name Canvas Venture Fund, with a new management company, Morgenthaler Technology Investment Co. In addition to an increased focus on algorithm engineering and digital health technologies, Third Rock Ventures has a history of investing in the Biotechnology sector. Early Stage VC, Later Stage VC, PE Growth/Expansion, Seed Round. WebAsk any biotech exec in the business of drug and device development about the funding environment these days, and you'll most likely hear the word "tough" inside of three seconds. WebCaroline Lembck is a distinguished executive in the biotechnology and finance industries, recognized for her remarkable achievements. No money was reported to have been raised, and a size was not disclosed for the fund. Largest investment: 17.9 million shares of Evotec worth $936 million at the time of its IPO, Total holding value of 2021 IPOs: $1.6 billion. (9), Current biopharma portfolio companies: CoMentis, Egalet, Epsilon 3 Bio, FF Pharma, GenSight Biologics, GlycoVaxyn, Levicept, Minerva Neurosciences, Molecular Partners, Novocure, Oncoethix, Sequenta, Versartis, XO1, Year established: 1996; successor to Index Securities, founded 1976, City (cities) where offices are located: Boston; Waltham, MA; San Francisco; Dublin; Also, @dogpatchlabs location in Dublin for biotechnology and technology startups, Fund size and status: About $4 billion under management across seven funds (10), Current fund: $450 million Polaris Venture Partners VII, closed Nov. 24; firm says on its website it continues to invest its sixth fund, $375 million Polaris Venture Partners VI, closed 2010 (10), Current biopharma portfolio companies: 480 Biomedical, Acceleron Pharma, Adimab, Advion, AgBiome, Alector, Alimera Sciences, Arsanis Biosciences, Arsenal Medical, aTyr Pharma, Cerulean Pharma, Editas, Fate Therapeutics, Genocea Biosciences, Hydra Biosciences, Ironwood, Kala Pharmaceuticals, KinDex Pharmaceuticals, Navitor Pharmaceuticals, NextCODE, Ocular Therapeutix, Promedior, Pulmatrix, Receptos, Scholar Rock, Selecta Biosciences, T2 Biosystems, Trevena, Visterra, Xtuit Pharmaceuticals, City (cities) where offices are located: Cambridge, MA; New York; Menlo Park, CA; So Paulo, Brazil; Herzliya Pituach, Israel; Bangalore, India, Fund size and status: More than $4 billion under management across eight funds (11), Current fund: $1.6 billion Bessemer Venture Partners VIII, closed 2011 (11), Current biopharma portfolio companies: Acceleron Pharma, AffyMax, Allena Pharmaceuticals, Cerulean Pharma, Flex Pharma, On-Q-ity, OvaScience, Oxagen, Proteon Therapeutics, Transave Inhalation Biopharmaceuticals, Verastem, City (cities) where offices are located: Cambridge, MA; Palo Alto, CA; Shanghai; London; and Geneva, Fund size and status: $4.2 billion under management across 12 funds. Founded in 2005, S3 Ventures is a venture capital firm based in Austin, Texas. Versant had a busy 2021: It was involved in five IPOs. Founded in 2012, Saudi Aramco Energy Ventures is the corporate venture capital arm of Aramco Oil Company. This was swiftly followed by another $300 million investment round in November 2021. Investment into biotech and health care boomed during the pandemic as thousands of venture capital firms turned their attention to breakthrough artificial intelligence, cancer-detection technology, mental health treatments, digital doctor visits, diagnostics and more. OrbiMed and. Which Current Shows Do You Actually Watch New Episodes Of Week By Week? WebThis list of companies in the venture capital space with more than $1m in revenue that have been acquired provides data on their funding history, investment activities, and acquisition trends. Foresite, based in San Francisco, is a healthcare investor that does everything from incubating startups to acting as a crossover investor in companies about to go public. Apeiron, Christian Angermayer's investment firm, is based in Malta and has $3.5 billion in assets under management. These VC firms led the most funding rounds for biotech startups this year between Jan. 1 and Dec. 1, according to Crunchbase data. The companys life science and healthcare investment portfolio spans the Biopharmaceutical, Biotechnology, medical equipment, services, and information and technology industries. The rise in transaction volume may be attributed to the increase in transaction sizes as the top firms receive extensive working capital. Massachusetts biopharma firms raised a record $13.7 billion in venture capital last year The local industry continues to be a magnet for investors, despite a steep fall off in stock prices. It is a part of the more prominent Novo Holding company, whose investments are more varied. Largest investment: 16.2 million shares of Graphite Bio worth $276 million at the time of its IPO, Total holding value of 2021 IPOs: $846 million. This years list shows the upward progression of VC firms; the lowest-ranked of this years firms had $1.25 billion under management, compared with more than $1.1 billion for the Top 30 Venture Capital Firms of 2013. Over $14 billion was invested in Biopharma startups globally in 2022, with 37 notable IPOs of VC-backed Biotech enterprises raising a total of $4.2 billion. Largest investment: 34.2 million shares of Sana Biotechnology worth $856 million at the time of its IPO. Founded in 2018, Cathexis Ventures is a corporate venture arm of Cathexis Holdings headquartered in Houston, Texas. The Indian startup/ VC ecosystem will truly come of age Always do your homework, check the VCs performance record, see whether you can tap into their network and expertise, and ensure the firm deals with companies in your stage. Current biopharma portfolio companies: Hyperion Therapeutics, OpGen, City (cities) where offices are located: Menlo Park, CA; Westport, CT; New York; Gurgaon, India; Herzliya Pituach, Israel, Fund size and status: $4.2 billion under management across nine funds, Current fund: $675 million Canaan Partners X, announced Oct. 16, Current biopharma portfolio companies: Aldea Pharmaceuticals, Arvinas, Axial Exchange, Chimerix, Chrono Therapeutics, CytomX, Dermira, Durata Therapeutics, Envisia Therapeutics, LQ3 Pharma, Marinus Pharmaceuticals, Novira Therapeutics, Sample6, Semnur Pharmaceuticals, Spinifex Pharmaceuticals, Theraclone Sciences, Tobira Therapeutics, VaxInnate, City (cities) where offices are located: New York; San Francisco; Mumbai; Shanghai; Herzliya, Israel, Fund size and status: Approximately $12 billion under management in five public funds, as well as private equity funds in North America/Europe, Asia, and Israel; and a Royalty Opportunities Fund launched 2011 to invest in healthcare royalty streams, Current fund: $325 million OrbiMed Asia Partners II, closed September; $735 million OrbiMed Private Investments V, closed October 2013, Current biopharma portfolio companies: Acceleron Pharma, Adaptimmune, Aerocrine, Adimab, Aerpio, Affimed, Alector, Amarin, Ambit Biosciences, Anthera, arGEN-X, ARMO BioSciences, Arsanis Biosciences, Arteaus, Audentes Therapeutics, Avitide, Bharat Serums and Vaccines, Biodel, BioLineRx, Cardioxyl, cCAM Biotherapeutics, Cerenis Therapeutics, Cleave Biosciences, Clementia, Dimension Therapeutics, Durata Therapeutics, Eddingpharm, GC-Rise Pharmaceutical, Good Start Genetics, Igenica, Intercept Pharmaceuticals, Invitae, Iroko Pharmaceuticals, Loxo Oncology, Mirati Therapeutics, Otic Pharma, Otonomy, OxOnc Development, PharmAbcine, Pieris, Principia Biopharma, ProNAi, RDD Pharma, RedHill Biopharma, Relypsa, Response BioMedical, Roka BioScience, Sage Therapeutics, Selecta Biosciences, Shasun, singulex, Symbionics Therapeutics, Waterstone Pharmaceuticals, #2. Who has the most invested in funding up-and-coming biotechs? Largest investment: 16.2 million shares of Theseus Pharmaceuticals worth $259 million at the time of its IPO, Total holding value of 2021 IPOs: $988.4 million. With $19 billion in assets under management, OrbiMed is set to be a leader next year as well. To date, over 70 of the companys life science products have received FDA approval. Biotech is just one piece of its portfolio Mubadala also invests in aerospace, renewable energy, real estate, and several other industries. The firm seeks to make minority investments in seed, early-stage, and later-stage companies. Does the firm have any background in technology similar to yours? Founding Partners Carl Soderstrom and Clay Heighten, MD. They have made over 177 investments in HealthTech, Biotechnology and HealthTech companies. Many investors contributed their efforts in early-stage Biotech to find the next Moderna. Boston-based RA Capital Management and New York-based OrbiMed ranked first and second, respectively, on the two lists compiled using Crunchbase data. RA Capital Management and OrbiMed led the way in both total dollars invested and the number of venture capital funding rounds led in the biotech industry last yearthe only two firms to make it onto both lists. Karuna parts ways with executive as it gears up for schizophrenia drug's high-profile launch. Medtech. That seventh fund closed $50 million higher than the $400 million offering amount that the firm stated back on June 17, when it disclosed its plan to raise the fund in a Form D filing with the U.S. Securities and Exchange Commission. The report predicts venture capital (VC) activity and performance for next year. Find the right companies, identify the right contacts, and connect with decision-makers with an all-in-one prospecting solution. Fierce Healthcare. The trend of increased biotech venture capital continues in 2021 with the newly announced fund NFX Bio. It is owned entirely by the Novo Nordisk Foundation, the holdings limited of the Novo Group. It is typical for venture capital firms to identify and back companies in high technology industries and so venture capital is most active in the fast-growing technology and life sciences or biotechnology fields. Largest investment: 9.6 million shares of Erasca worth $153 million at the time of its IPO, Total holding value of 2021 IPOs: $539.4 million. The firm seeks to invest in the media, software, and healthcare sectors. The Baltimore-based company was active in a handful of 2021 biotech IPOs, including Evotec, Longboard Pharmaceuticals, and Imago BioSciences. Apparel and Accessories, Beverages, Consumer Durables, Food Products, Healthcare, Other Restaurants, Hotels and Leisure, Services (Non-Financial), Software, Co-founders and General Partners Genevieve Gilbreath and Dan Graham. Polaris describes the seventh fund as a partnership investing in technology and healthcare. See: http://myemail.constantcontact.com/Announcing-Fund-VII.html?soid=1106633098844&aid=84wvr4fxTTs The Legal 500 > United States > United States > M&A/corporate and commercial > Venture capital and emerging companies. Additionally, Bain Capital Crypto closed a $500 million fund in March 2022, and the firm announced a $2.4 billion Tech Opportunities fund earlier this month. According to its website, the business has 36 IPOS and $3.2 billion under control. Blackstone, one of the largest private venture capital firms, founded Blackstone Life Sciences in 2018 after acquiring Clarus Ventures, an equity firm with $2.6 billion in assets. RA Capital led the companys $336 million Series C ahead of the companys August IPO, though the firm hadnt participated in the companys earlier funding rounds. Healthcare, Security Services (B2B), Social Content, Software, Buyout/LBO, Debt General, Early Stage VC, Later Stage VC, PE Growth/Expansion, Recapitalization, Seed Round. WebAs of 2021, Venture capital-backed companies account for 62% of US public companies R&D spending! Founded in 2009, Capital Factory is a venture capital firm and an accelerator based in Austin, Texas. In addition to holding shares in four biotechs that went public this year, Foresite was involved in two SPAC deals for the biomarker and diagnostics firm SomaLogic and the protein-sequencing company Quantum-Si that went through this year, giving it more capital to deploy in 2022. WebThe 45 most important VCs in Texas, according to other VCs. Fund size and status: More than $14 billion in committed capital across 14 funds, Current fund: $2.6 billion New Enterprise Associates 14 L.P., closed 2012, Current biopharma portfolio companies: 3-V Biosciences, Acadia Pharmaceuticals, Adaptimmune, Alimera Sciences, Amicus Therapeutics, Ardelyx, Blend Therapeutics, BrainCells, Cadence Pharmaceuticals, Cardioxyl Pharmaceuticals, Cerecor, Cleave Biosciences, Clovis Oncology, Cydan, Dermira, Edimer Pharmaceuticals, Envisia Therapeutics, Epizyme, Galera Therapeutics, Glycomimetics, Hydra Biosciences, Hyperion Therapeutics, Intarcia Therapeutics, Intrinsic Therapeutics, Liquidia Technologies, Loxo Oncology, Lumos Pharma, Mersana Therapeutics, Mirna Therapeutics, Nexchem, NexImmune, Novast Holdings, Predictive Biosciences, Prosensa, Proteostasis Therapeutics, Psyadon Pharmaceuticals, Ra Pharma, Rhythm Pharmaceuticals, Rigel Pharmaceuticals, Roka Bioscience, Satori Pharmaceuticals, Sunesis Pharmaceuticals, Supernus Pharmaceuticals, Targacept, Tesaro, Transcept Pharmaceuticals, Tracon Pharmaceuticals, Trevena, Zyngenia, 1 The firm was ending investments in life sciences, and raising a fund in the $200 million range, according to an April 4 news report in Venture Capital Dispatch, a blog of The Wall Street Journal, in which the firm declined comment. 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